Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

4136-95-2 - 2,4,6-Trichlorobenzoyl chloride, 98% - L14159 - Alfa Aesar

L14159 2,4,6-Trichlorobenzoyl chloride, 98%

Numéro CAS
4136-95-2
Synonymes

Dimensions Prix ($) Quantité Disponibilité
5g 44,70
25g 177,30
Ajouter au panier Ajouter au devis en vrac Afficher l'article

2,4,6-Trichlorobenzoyl chloride, 98%

MDL
MFCD00075323

Propriétés chimiques

Formule
C7H2Cl4O
Poids formulaire
243.91
Point d'ébullition
107-108°/6mm
Point d'éclair
>110°(230°F)
Densité
1.561
Indice de réfraction
1.5750
Sensibilité
Moisture Sensitive
Solubilité
Reacts with water.

Applications

2,4,6-Trichlorobenzoyl chloride is used in the preparation of γ-lactone and δ-lactone, aliphatic aromatic anhydrides, required for the synthesis of amphiphilic hyaluronan, mixed anhydride, required for the synthesis of angelate esters, synthesis of both spongistatin 1 and spongistatin 2 and large-ring lactones in high yields.

Notes

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. It is sensitive to moisture. Incompatible with strong bases and strong oxidizing agents.

Références bibliographiques

Gloria Huerta-Angeles.; Martin Bobek.; Eva P?íkopová.; Daniela Šmejkalová.; Vladimír Velebný. Novel synthetic method for the preparation of amphiphilic hyaluronan by means of aliphatic aromatic anhydrides. .Carbohydrate Polymers 2014, 111 883-891.

Machiko Ono.; Keisuke Kato.; Hiroyuki Akita. Synthesis of γ- and δ-lactone natural products by employing a trans-cis isomerization/lactonization strategy. Chemical & Pharmaceutical Bulletin. 2013, 61 (4), 464-470.

Reagent, introduced by Yamaguchi, which forms mixed anhydrides with acids, useful in the synthesis of esters: Bull. Chem. Soc. Jpn., 52, 1989 (1979), or lactones including macrolides: Chem. Lett., 1021 (1979). Superior to mesitylenesulfonyl chloride for macrolactonization, which has been achieved in the presence of DMAP without the need for high dilution: J. Org. Chem., 55, 7 (1990); Tetrahedron Lett., 31, 6367 (1990).

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Mentions de prudence: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Beilstein
2050280
Classe de danger
8
Groupe d'emballage
II
Code tarifaire harmonisé
2916.39
TSCA
No

Recommandé

  • A10173

    Trifluoromethanesulfonic acid, 98+%
  • A11218

    2-Methylcyclohexane-1,3-dione, 98+%
  • L14342

    Chromium(II) chloride, anhydrous, 97%
  • 36501

    Methanol-d<sub>4</sub>, 99.8%(Isotopic)
  • 41841

    Toluene, anhydrous, 99.8%, packaged under Argon in resealable ChemSeal™ bottles

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire