Consentement d'utilisation des Cookies

J'accepte Notre site sauvegarde des traceurs textes (cookies) sur votre appareil afin de vous garantir de meilleurs contenus et à des fins de collectes statistiques.Vous pouvez désactiver l'usage des cookies en changeant les paramètres de votre navigateur. En poursuivant votre navigation sur notre site sans changer vos paramètres de navigateur vous nous accordez la permission de conserver des informations sur votre appareil.

50-91-9 - 5-Fluoro-2'-deoxyuridine, 98+% - 2'-Deoxy-5-fluorouridine - Floxuridine - L16497 - Alfa Aesar

L16497 5-Fluoro-2'-deoxyuridine, 98+%

Numéro CAS
50-91-9
Synonymes
2'-Deoxy-5-fluorouridine
Floxuridine

Dimensions Prix ($) Quantité Disponibilité
100mg 79,21
500mg 261,62
Ajouter au panier Ajouter au devis en vrac Afficher l'article

5-Fluoro-2'-deoxyuridine, 98+%

MDL
MFCD00006530
EINECS
200-072-5

Propriétés chimiques

Formule
C9H11FN2O5
Poids formulaire
246.20
Point de fusion
148-151°
Solubilité
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.

Applications

5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.

Notes

Store in a cool place.Incompatible with strong oxidizing agents and strong bases.

Références bibliographiques

Rooney, J. P.; Luz, A. L.; Gonzalez-Hunt, C. P.; Bodhicharla, R.; Ryde, I. T.; Anbalagan, C.; Meyer, J. N. Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. Exp. Gerontol. 2014, 56, 69-76.

Kruspe, S.; Hahn, U. An Aptamer Intrinsically Comprising 5-Fluoro-2'-deoxyuridine for Targeted Chemotherapy. Mol. BioSyst. 2014, 53 (39), 10541-10544.

Mentions de danger et de prudence du SGH

Mentions de danger (UE): H360-H341-H302

May damage fertility or the unborn child. Suspected of causing genetic defects. Harmful if swallowed.

Mentions de prudence: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Autres références

Merck
14,4112
Beilstein
2645818
Classe de danger
6.1
Groupe d'emballage
III
Code tarifaire harmonisé
2934.99
TSCA
No
RTECS
YU7535000

Recommandé

  • A10926

    Diethylenetriaminepentaacetic acid, 98+%
  • A11079

    Sodium butyrate, 98+%
  • A12075

    Cacodylic acid, 98%
  • 11287

    Gadolinium(III) chloride hexahydrate, REacton®, 99.99% (REO)
  • 14248

    Iodine, crystalline, 99.5%

Consulté récemment

Produits chimiques

Sciences de la vie

Métaux et matériaux

Catalyseurs

Analytique et matériel de laboratoire