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147-24-0 - Diphenhydramine hydrochloride, 99% - A10136 - Alfa Aesar

A10136 Diphenhydramine hydrochloride, 99%

Codice CAS
147-24-0
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
50g 26,90
250g 84,40
1000g 291,00
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Diphenhydramine hydrochloride, 99%

MDL
MFCD00012479
EINECS
205-687-2

Proprietà chimiche

Formula
(C6H5)2CHOCH2CH2N(CH3)2•HCl
Peso formula
291.82
Punto di fusione
168-169°
Sensibilità
Light Sensitive
Solubilità
Soluble in water, dimethyl sulfoxide, dimethylformamide, methanol and ethanol.

Applicazioni

A histamine H1 receptor antagonistDiphenhydramine hydrochloride acts as a sodium channel blocker. It is used as a histamine H1-receptor antagonist. Further, it is used as a sedative, hypnotic, antiemetic, antitussive and pruritus. It is employed in the treatment of allergic conditions. In addition to this, it is used as an active ingredient in common cold preparations.

Note

Incompatible with strong oxidizing agents, strong acids and alkalis.

Letteratura

Miao, C.; Zhang, A.; Xu, Y.; Chen, S.; Ma, F.; Huang, C.; Jia, N. An ultrasensitive electrochemiluminescence sensor for detecting diphenhydramine hydrochloride based on l-cysteine-functionalized multiwalled carbon nanotubes/gold nanoparticles nanocomposites. Sens. Actuators, B 2015, 213, 5-11.

Jengathe, S. P.; Dhondge, S. S.; Paliwal, L. J.; Tangde, V. M.; Mondal, S. Effect of sodium chloride and myo-inositol on diphenhydramine hydrochloride drug in aqueous solution at different temperatures: Volumetric and acoustic approach. J. Chem. Thermodyn. 2015, 87, 78-87.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H351-H361-H302-H315-H319-H335

Suspected of causing cancer. Suspected of damaging fertility or the unborn child. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P301+P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Classe di rischio
6.1
Gruppo di imballaggio
III
Codice tariffe armonizzato
2922.19
TSCA
No

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