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370-81-0 - Bis(cyclohexanone) oxaldihydrazone, 98% - Oxalic acid bis(cyclohexylidenehydrazide) - Cuprizon I - A10628 - Alfa Aesar

A10628 Bis(cyclohexanone) oxaldihydrazone, 98%

Codice CAS
370-81-0
Sinonimi
Oxalic acid bis(cyclohexylidenehydrazide)
Cuprizon I

Dimensioni Prezzo ($) Quantità Disponibilità
25g 36,18
100g 111,34
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Bis(cyclohexanone) oxaldihydrazone, 98%

MDL
MFCD00001659
EINECS
206-729-2

Proprietà chimiche

Formula
C14H22N4O2
Peso formula
278.36
Punto di fusione
208-212°
Solubilità
Soluble in alcohol. Insoluble in water.

Applicazioni

Bis(cyclohexanone) oxaldihydrazone is used in the quantitative spectroscopic determination of copper. It is also essential for the experimental study of mitochondrial metabolism. It is used to study the human demyelinating diseases such as multiple sclerosis and components of neuroinflammation. Further, it acts as ligand and catalyzes Ullmann-type C-N bond forming reactions in the presence of copper salt.

Note

Incompatible with strong oxidizing agents and strong bases.

Letteratura

Reagent for spectrophotometric determination of Cu(II): Anal. Chem., 38, 911 (1966).

Krauspe, B. M.; Dreher, W.; Beyer, C.; Baumgartner, W.; Denecke, B.; Janssen, K.; Langhans, C. D.; Clarner, T.; Kipp, M. Short-Term Cuprizone Feeding VerifiesN-Acetylaspartate Quantification as a Marker of Neurodegeneration. J. Mol. Neurosci. 2015, 55 (3), 733-748.

Slowik, A.; Schmidt, T.; Beyer, C.; Amor, S.; Clarner, T.; Kipp, M. The sphingosine 1-phosphate receptor agonist FTY720 is neuroprotective after cuprizone-induced CNS demyelination. Br. J. Pharmacol. 2015, 172 (1), 80-92.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
2388004
Codice tariffe armonizzato
2928.00
TSCA
Yes
RTECS
RO2520000

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