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1633-82-5 - 3-Chloropropanesulfonyl chloride, 98+% - 3-Chloropropylsulfonyl chloride - A10631 - Alfa Aesar

A10631 3-Chloropropanesulfonyl chloride, 98+%

Codice CAS
1633-82-5
Sinonimi
3-Chloropropylsulfonyl chloride

Dimensioni Prezzo ($) Quantità Disponibilità
10g 67,36
50g 225,00
250g 809,60
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3-Chloropropanesulfonyl chloride, 98+%

MDL
MFCD00007463
EINECS
216-646-3

Proprietà chimiche

Formula
C3H6Cl2O2S
Peso formula
177.05
Punto di ebollizione
70°/0.5mm
Punto di infiammabilità
>110°(230°F)
Densità
1.456
Indice di rifrazione
1.4900
Sensibilità
Moisture Sensitive
Solubilità
Soluble in dichloromethane, ethyl Acetate and hexane.

Applicazioni

3-Chloropropanesulfonyl Chloride is an intermediate used in the preparation of many enzymatic inhibitors. It is also used in the generation and trapping of the derived sulfene with imines and glyoxylates in the presence of chinchona alkaloids provide chiral sultams and sultones. It is mainly used for the synthesis of pharmaceutical intermediates.

Note

Store at -20°C. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Containers which are opened must be carefully resealed and kept upright to prevent leakage. Moisture sensitive. Keep away from alcohols, strong bases, oxidizing agents.

Letteratura

RK Bakshi.; Q Hong.; R Tang.; RN Kalyani. Optimization of a privileged structure leading to potent and selective human melanocortin subtype-4 receptor ligands. span class="italictxt"> Bioorganic & Medicinal Chemistry Letters. 2006 16, (5) , 1130-1133.

C Shah.; L McAtee.; JG Breitenbucher.; D Rudolph. Novel human histamine H 3 receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 2002 12, (22) , 3309-3312.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Dichiarazioni precauzionali: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
1754119
Classe di rischio
8
Gruppo di imballaggio
II
Codice tariffe armonizzato
2904.90
TSCA
No
RTECS
TZ6670000

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