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872-85-5 - Pyridine-4-carboxaldehyde, 97% - Isonicotinaldehyde - A10656 - Alfa Aesar

A10656 Pyridine-4-carboxaldehyde, 97%

Codice CAS
872-85-5
Sinonimi
Isonicotinaldehyde

Dimensioni Prezzo ($) Quantità Disponibilità
25g 28,98
100g 81,97
500g 255,99
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Pyridine-4-carboxaldehyde, 97%

MDL
MFCD00006425
EINECS
212-832-3

Proprietà chimiche

Formula
C6H5NO
Peso formula
107.11
Punto di fusione
-4°
Punto di ebollizione
198°
Punto di infiammabilità
75°(167°F)
Densità
1.132
Indice di rifrazione
1.5440
Sensibilità
Air & Light Sensitive
Solubilità
Soluble in water (20 mg/ml at 20°C), ethanol and acetone.

Applicazioni

Pyridine-4-carboxaldehyde is an heterocyclic building block used for the synthesis of various pharmaceutical compounds, such as new 1,4-dihydropyridin-4-yl-phenoxyacetohydrazones, having anticonvulsant and anti-inflammatory properties.

Note

It is air and light sensitive. Incompatible with oxidizing agents.

Letteratura

Nand K.Singh; Rajesh Tripathi. Synthesis and structural characterization of 3d-metal complexes of pyridine-4-carboxaldehyde thionicotinoyl hydrazone. Transition Metal Chemistry. 1988, 13, (5),346-350

 

A.Martin; B.Lucke; H.J.Niclas; A.Forster. Vapor-phase oxidation of 4-picoline to pyridine-4-carboxaldehyde on a vanadium phosphate catalysts. Reaction Kinetics and Catalysis Letters. 1991, 43, (2),583-588

In the presence of DBU, converts amines to carbonyl compounds, e.g. benzylamines to benzaldehydes: Synthesis, 756 (1982):

The reaction is also useful for the conversion of ɑ-amino acids to ɑ-keto acids.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H317-H335-H227

Causes skin irritation. Causes serious eye irritation. May cause an allergic skin reaction. May cause respiratory irritation. Combustible liquid.

Dichiarazioni precauzionali: P210-P261-P280-P305+P351+P338-P304+P340-P362-P312-P363-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
105342
Codice tariffe armonizzato
2933.39
TSCA
Yes
RTECS
NR9400000

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