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501-30-4 - Kojic acid, 99% - 5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one - A10760 - Alfa Aesar

A10760 Kojic acid, 99%

Codice CAS
501-30-4
Sinonimi
5-Hydroxy-2-(hydroxymethyl)-4H-pyran-4-one

Dimensioni Prezzo ($) Quantità Disponibilità
5g 40,17
25g 143,10
100g 460,80
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Kojic acid, 99%

MDL
MFCD00006580
EINECS
207-922-4

Proprietà chimiche

Formula
C6H6O4
Peso formula
142.11
Punto di fusione
152-155°
Solubilità
Soluble in water, acetone (freely soluble), ethanol (freely soluble), methanol, DMSO, ethyl acetate (slightly soluble), chloroform (slightly soluble), pydidine (slightly soluble) and ether (slightly soluble). Insoluble in benzene.

Applicazioni

Kojic acid may be used on cut fruits to prevent oxidative browning, in seafood to preserve pink and red colors and in cosmetics to lighten skin. It is used to treat skin diseases like melasma as it has antibacterial and antifungal properties. It is used as a chelation agent that inhibits melanin production and also as a tyrosine kinase inhibitor.

Note

Should be stored at room temperature. Stable under recommended storage conditions. Incompatible with oxidizing agents and bases.

Letteratura

Juana Cabenes; Soledad Chazarra; Francisco Garcia-Carmona. Kojic acid, a cosmetic Skin whitening agent, is a slow-binding inhibitor of catecholase activity of tyrosinase. Journal of Pharmacy and Pharmacology. 1994, 46, (12),982-985

 

Jon S.Chen; Cheng I.Wei; Marty R.Marshall. Inhibition mechanism of kojic acid on polyphenol oxidase. J. Agric. Food Chem. 1991, 39, (11),1897-1901

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H351

Suspected of causing cancer.

Dichiarazioni precauzionali: P201-P281-P202-P308+P313-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Do not handle until all safety precautions have been read and understood. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,5317
Beilstein
120895
Codice tariffe armonizzato
2941.90
TSCA
No
RTECS
UQ0875000

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