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The Schiff bases(2-Benzoylpyridine ) and copper(II) complexes display moderate antifungal activities. 2-Benzoylpyridine is an aromatic substituent which has selective antiproliferative effects, with the majority having greater antineoplastic activity. Reaction of 2-benzoylpyridine N(4)-phenyl thiosemicarbazone (HL) with a variety of copper salts yielded a series of copper(II) complexes of the type [CuLX]. Complexes of 2-benzoylpyridine thiosemicarbazone (H2Bz4DH) as well as of its N(4)-methyl (H2Bz4Me) and N(4)-phenyl (H2Bz4Ph) analogues with iron(II), nickel(II) and zinc(II) were characterized by a variety of spectroscopic techniques.
Angel A. Recio Despaigne,; Jeferson G. Da Silva, Ana Cerúlia M. Do Carmoa, Oscar E. Pirob, Eduardo E. Castellanoc, Heloisa Beraldoa, .Copper(II) and zinc(II) complexes with 2-benzoylpyridine-methyl hydrazone. Journal of Molecular Structure. 2009, 920 (1-3), 97-102.
M.E. Hossaina,; M.N. Alam,; J. Begum,; M. Akbar Ali,; M. Nazimuddin,; F.E. Smith,; R.C. Hynes.The preparation, characterization, crystal structure and biological activities of some copper(II) complexes of the 2-benzoylpyridine Schiff bases of S-methyl- and S-benzyldithiocarbazate. Inorganica Chimica Acta. 1996, 249(2), 207-213
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.