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121-60-8 - 4-Acetamidobenzenesulfonyl chloride, 98+% - N-Acetylsulfanilyl chloride - A11511 - Alfa Aesar

A11511 4-Acetamidobenzenesulfonyl chloride, 98+%

Codice CAS
121-60-8
Sinonimi
N-Acetylsulfanilyl chloride

Dimensioni Prezzo ($) Quantità Disponibilità
50g 14,00
250g 28,20
1000g 76,10
5000g 297,00
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4-Acetamidobenzenesulfonyl chloride, 98+%

MDL
MFCD00007442
EINECS
204-485-1

Proprietà chimiche

Formula
C8H8ClNO3S
Peso formula
233.67
Punto di fusione
ca 146° dec.
Sensibilità
Moisture Sensitive
Solubilità
It is slightly in water. But soluble in benzene, chloroform and ether.

Applicazioni

N-Acetylsulfanilyl chloride is used in the preparation of sulfanilamide and its derivatives which are intermediates to produce sulfa drugs. They are used in the prevention and treatment of bacterial infections, diabetes mellitus, edema, hypertension, and gout. It is also used as a Pharma raw material. N-Acetylsulfanilyl chloride widely used in the fields of dye, medicine, mainly used for preparation of Sulfanilamide, Sulfanilylureal, Sulfatolamide, Sulphathiourea , Sulfaguanidine and Sulfacetamide and etc.

Note

Stable under ordinary conditions. Moisture sensitive.Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong oxidizing agents, Strong bases.

Letteratura

Shinsaku Fujita.;  Kazuya Sano. Reduction of quinones and quinonemonosulfonimides with N,N-diethylhydroxylamine. J. Org. Chem. 1979, 44, (15), 2647-2651.

Richard E. Donaldson.; P. L. Fuchs. alpha.'-Functionalization of .beta.,.gamma.-unsaturated cyclohexenones. Utilization of silyl enol ethers produced from the lithium/ammonia reduction of silyl aryl ethers. J. Org. Chem. 1977, 42, (11), 2032-2034.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Dichiarazioni precauzionali: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P363-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,103
Beilstein
746676
Classe di rischio
8
Gruppo di imballaggio
II
Codice tariffe armonizzato
2924.29
TSCA
Yes
RTECS
DB8837500

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