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89-73-6 - Salicylhydroxamic acid, 99% - 2-Hydroxybenzohydroxamic acid - A11528 - Alfa Aesar

A11528 Salicylhydroxamic acid, 99%

Codice CAS
89-73-6
Sinonimi
2-Hydroxybenzohydroxamic acid

Dimensioni Prezzo ($) Quantità Disponibilità
10g 25,20
25g 47,00
50g 82,70
100g 155,00
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Salicylhydroxamic acid, 99%

MDL
MFCD00002110
EINECS
201-934-3

Proprietà chimiche

Formula
C7H7NO3
Peso formula
153.14
Punto di fusione
ca 170° dec.
Solubilità
It is soluble in water.

Applicazioni

It is widely used for a variety of roles in biology and medicine as a chelating therapy. It inhibits bacterial or fungi growth by interfering with iron uptake. It is also active as a inhibitor of enzyme involved in tumour growths. These compounds are used as extractants for the separation of valuable metals or minerals including copper, lead, gold, other rare earth metals and kaolin. Hydroxamic acids are also used to produce corresponding isocyanates by dehydration followed by rearrangement reaction. It is also used as a common ligand utilized in the synthesis of metallacrowns.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Incompatible to Strong bases. Stable under normal conditions.

Letteratura

Curt A. Davey & Roger E. Fenna. 2.3 Å Resolution X-ray Crystal Structure of the Bisubstrate Analogue Inhibitor Salicylhydroxamic Acid Bound to Human Myeloperoxidase:? A Model for a Prereaction Complex with Hydrogen Peroxide. Biochemistry. 1996, 35, (33), 10967-10973.

Mark L. Stolowitz.; Clarence Ahlem.; Karin A. Hughes.; Robert J. Kaiser.; Edward A. Kesicki.; Guisheng Li.; Kevin P. Lund.; Steven M. Torkelson.; and Jean P. Wiley. Phenylboronic Acid-Salicylhydroxamic Acid Bioconjugates. 1. A Novel Boronic Acid Complex for Protein Immobilization. Bioconjugate Chem. 2001, 12, (2), 229-239.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H341-H315-H319-H335-H303

Suspected of causing genetic defects. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation. May be harmful if swallowed.

Dichiarazioni precauzionali: P201-P261-P280-P281-P305+P351+P338-P304+P340-P362-P312-P405-P501a

Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Use personal protective equipment as required. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,8331
Beilstein
1210520
Codice tariffe armonizzato
2928.00
TSCA
No
RTECS
VO6870000

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