A11626 4,4'-Dimethoxytrityl chloride, 98%
SDS
| Stock No. | Dimensioni | Prezzo ($) | Quantità | Disponibilità |
|---|---|---|---|---|
| A11626-06 | 5g | 40,90 |
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| A11626-14 | 25g | 127,00 |
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| A11626-22 | 100g | 437,00 |
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4,4'-Dimethoxytrityl chloride, 98%
Proprietà chimiche
Applicazioni
4,4'-Dimethoxytrityl chloride is used as a protective reagent for oligonucleotide synthesis. It is used for selective protection and deprotection procedures for thiol and hydroxy groups in nucleoside derivatives.
Note
Letteratura
Ingale, S. A.; Leonard, P.; Tran, Q. N.; Seela, F. Duplex DNA and DNA-RNA Hybrids with Parallel Strand Orientation: 2'-Deoxy-2'-fluoroisocytidine, 2'-Deoxy-2'-fluoroisoguanosine, and Canonical Nucleosides with 2'-Fluoro Substituents Cause Unexpected Changes on the Double Helix Stability. J. Org. Chem. 2015, 80 (6), 3124-3138.
Vemekar, S. K. V.; Qiu, L.; Zhang, J.; Kankanala, J.; Li, H.; Geraghty, R. J.; Wang, Z. 5'-Silylated 3'-1,2,3-triazolyl Thymidine Analogues as Inhibitors of West Nile Virus and Dengue Virus. J. Med. Chem. 2015, 58 (9), 4016-4028.
Rischio GHS e dichiarazioni precauzionali
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.
