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A12093 Tri(o-tolyl)phosphine, 98+%

Codice CAS
6163-58-2
Sinonimi
Tris(2-methylphenyl)phosphine
Tris(o-tolyl)phosphine

Stock No. Dimensioni Prezzo ($) Quantità Disponibilità
A12093-03 1g 22,00
A12093-06 5g 71,90
A12093-14 25g 268,00
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Tri(o-tolyl)phosphine, 98+%

MDL
MFCD00008514
EINECS
228-193-9

Proprietà chimiche

Formula
C21H21P
Peso formula
304.37
Punto di fusione
122-127°
Storage & Sensitivity
Air Sensitive. Ambient temperatures.
Solubilità
Soluble in alcohol. Slightly soluble in cold water. Insoluble in water.

Applicazioni

Tri(o-tolyl)phosphine is used in a ruthenium-catalyzed direct amination of alcohols. It is also used in Suzuki reaction. Further, it is used in the preparation of tri-ortho-phosphinselenide by reacting with selenium as a reagent. In addition to this, it acts as a ligand in coordination chemistry.

Note

Light sensitive. Incompatible with strong oxidizing agents.

Letteratura

Preferred phosphine ligand for use in combination with Pd salts in the Heck-type coupling reactions of vinylic halides. For examples, see Palladium(II)­ acetate, 10516. For a review of the Heck reaction, see: Org. React., 27, 345 (1982).

The Pd-catalyzed amination of bromoarenes with 1-Boc-piperazine, L13363, in the presence of this ligand, provides a route to arylpiperazines of potential pharmacological interest: Tetrahedron Lett., 39, 2219 (1998).

Chang, C. H.; Chen, M. H.; Du, W. S.; Gliniak, J.; Lin, J. H.; Wu, H. H.; Chan, H. F.; Yu, J. S. K.; Wu, T. K. A Ruthenium-Based Biomimetic Hydrogen Cluster for Efficient Photocatalytic Hydrogen Generation from Formic Acid. Chem. Eur. J. 2015, 21 (17), 6617-6622.

Lennartson, A.; Håkansson, M. A missing link between chiral four-and five-coordinate complexes. New J. Chem. 2015, 39 (5), 3353-3356.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
661212
Codice tariffe armonizzato
2931.39
TSCA
Yes

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