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Used as a protein denaturantUrea is a raw fabric for the manufacture of organic resins and is used as protein denaturant sealant and in agriculture, dyes, fuels, functional fluids, intermediates, paint additives and coating additives. Urea is used as a nitrogen-release fertilizer, on-corroding alternative to rock salt for road de-icing, browning agent in factory-produced pretzels, cloud seeding agent, a deep eutectic solvent and type of ionic liquid.
Widely used in diazotization reactions for the destruction of excess HNO2.
For the one-pot conversion of carboxylic acids to nitriles, by heating with urea in the presence of 1.5-2.0 moles of sulfamic acid, see: Chimia, 25, 94 (1971).
For a procedure for conversion of carboxylic acids to primary amides by heating with urea, see: Org. Synth. Coll., 3, 768 (1955); 4, 513 (1963).
Reacts with alcohols on prolonged heating to give alkyl carbamates; see, e.g.: Org. Synth. Coll., 1, 140 (1941).
Zhang, Y.; Han, C.; Nadagouda, M. N.; Dionysiou, D. D. The fabrication of innovative single crystal N, F-codoped titanium dioxide nanowires with enhanced photocatalytic activity for degradation of atrazine. Appl. Catal. B 2015, 168-169, 550-558.
Amendola, V.; Fabbrizzi, L.; Mosca, L. Anion recognition by hydrogen bonding: urea-based receptors. Chem. Soc. Rev. 2010, 39, 3889-3915.