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Sulfadiazine is used as an antibacterial. It is a short-acting sulfonamide that is commonly used with pyrimethamine to treat toxoplasmosis in patients with acquired immunodeficiency syndrome. It is also used to treat newborns with congenital infections and to control acute infections when studying murine models of reactivated toxoplasmosis. It is It eliminates bacteria that cause infections by stopping the production of folic acid inside the bacterial cell, and is commonly used to treat urinary tract infections (UTIs)
Charles L. Fox Jr.; Shanta M. Modak. Mechanism of Silver Sulfadiazine Action on Burn Wound Infections. Antimicrob. Agents Chemother. 1974, 5 (6), 582-588.
Shanta M. Modak.; Charles L. Fox Jr. Binding of silver sulfadiazine to the cellular components of Pseudomonas aeruginosa. Biochemical Pharmacology. 1973, 22 (19), 2391-2404.
Dichiarazioni di rischio (UE): H302-H315-H319-H334-H317-H335
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. May cause respiratory irritation.
Dichiarazioni precauzionali: P284-P261-P280a-P305+P351+P338-P405-P501a
Wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.