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50-78-2 - O-Acetylsalicylic acid, 99% - 2-Acetoxybenzoic acid - A12488 - Alfa Aesar

A12488 O-Acetylsalicylic acid, 99%

Codice CAS
50-78-2
Sinonimi
2-Acetoxybenzoic acid

Dimensioni Prezzo ($) Quantità Disponibilità
100g 17,64
500g 40,27
2500g 147,29
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O-Acetylsalicylic acid, 99%

MDL
MFCD00002430
EINECS
200-064-1

Proprietà chimiche

Formula
C9H8O4
Peso formula
180.15
Punto di fusione
133-140°
Punto di infiammabilità
250°(482°F)
Densità
1.400
Solubilità
Soluble in 100% ethanol (80mg/ml), DMSO (41mg/ml) or dimethyl formamide (30mg/ml); slightly soluble in Phosphate-buffered saline (PBS), pH 7.2 (2.7mg/ml).

Applicazioni

O-Acetylsalicylic acid is the prototypical analgesic used in the treatment of mild to moderate pain. acts as an inhibitor of cyclooxygenase which results in the inhibition of the biosynthesis of prostaglandins. Aspirin also inhibits platelet aggregation and is used in the prevention of arterial and venous thrombosis. Along with sodium salicylate (sc-3520), aspirin has been shown to block the long terminal repeat from the human immunodeficiency virus and the Ig κ enhancer from NFκB dependent transcription.

Note

Store at room temperature. Ensure good ventilation.

Letteratura

D W Gilroy et. Al. Differential effects of inhibitors of cyclooxygenase (cyclooxygenase 1 and cyclooxygenase 2) in acute inflammation. Eur. J. Pharmacol. 1998, 355 (2-3),211-217.

K Schrör. Aspirin and platelets: the antiplatelet action of aspirin and its role in thrombosis treatment and prophylaxis. Seminars in Thrombosis and Hemostasis. 1997, 23 (4),349-356.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H315-H319-H335

Harmful if swallowed. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,851
Beilstein
779271
Codice tariffe armonizzato
2918.22
TSCA
Yes
RTECS
VO0700000

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