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Indole-3-carboxylic acid is used as a raw material in synthesis. The structures of the derivatives of indole-3-carboxylic acid were studied using gas chromatography with high resolution mass spectrometry (GC-HRMS), ultra-high performance liquid chromatography in combination with high resolution tandem mass spectrometry (UHPLC-HRMS), nuclear magnetic resonance spectroscopy (NMR) and Fourier transform infrared spectroscopy. Reactant for preparation of: Anticancer agents, Derivatives of amino acids and peptides, Serotonin 5-HT4 receptor antagonists, Primary acylureas, Inhibitors of Gli1-mediated transcription in the Hedgehog pathway, Serotonin 5-HT6 antagonists, Very Late Antigen-4 (VLA-4) sntagonists, EphB3 receptor tyrosine kinase inhibitors, Potential Therapeutic Agent for Alzheimer?s Disease, Vinyl ester pseudotripeptide proteasome inhibitors
G Smith.; UD Wermuth.; PC Healy. Indole-3-carboxylic acid. Acta Crystallographica Section E. 2003, E59, (1), 1776-1777.
G Quartarone.; M Battilana.; L Bonaldo.; T Tortato. Investigation of the inhibition effect of indole-3-carboxylic acid on the copper corrosion in 0.5 MH 2 SO 4. Corrosion Science. 2008, 50, (12), 3467-3474.
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.