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4-Chlorobenzaldehyde is used as an intermediate for the manufacture of dyestuffs, optical brighteners, pharmaceuticals, agricultural chemicals and metal finishing products.
Işul Akmehmet Balcio?lu; Nicola Getoff. Advanced oxidation of 4-chlorobenzaldehyde in water by UV-light, ozonation and combination of both methods. Chemosphere. 1998, 36(9), 1993-2005.
Işul Akmehmet Balcio?lu; Nicola Getoff; Miray Bekbölet. A comparative study for the synergistic effect of ozone on the γ-irradiated and photocatalytic reaction of 4-chlorobenzaldehyde. Journal of Photochemistry and Photobiology A: Chemistry. 2000, 135(2-3), 229-233.
The nucleophilic (halex) substitution of the chloro substituent by F- can be achieved in good yield by high temperature reaction with KF in tetramethylene sulfone in the presence of Tetraphenylphosphonium bromide, A15860, as a thermally stable phase-transfer catalyst. This method is general for chloro substituents activated by an ortho- or para-aldehyde group: Chem. Lett., 1355 (1988).
Dichiarazioni di rischio (UE): H302-H315-H319
Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.
Dichiarazioni precauzionali: P273-P280h-P305+P351+P338
Avoid release to the environment. Wear protective gloves/clothing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.