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Sodium fluoride is used as a steel degreasing agent and in tin electroplating, flux, heat treating salt compositions, fluoridation of drinking water, removing HF from exhaust systems to reduce air pollution, and frosting glasses. It serves as a source of fluoride ion in several applications including it use in synthetic chemistry, for example in Finkelstein reaction for preparating fluoro compounds, desilylation in sensitive organic compounds, metallurgy, and reaction with electrophilic chlorides. It has medical and other applications including complexing of magnesium ions.
Reviews: Fluoride ion as a base in organic synthesis: Chem. Rev., 80, 429 (1980). Alkali metal fluorides in organic synthesis: Synthesis, 169 (1983). See also Potassium fluoride, 14130.
Songsiripradubboon, S.; Hamba, H.; Trairatvorakul, C.; Tagami, J. Sodium fluoride mouthrinse used twice daily increased incipient caries lesion remineralization in an in situ model. J. Dentistry 2014, 42 (3), 271-278.
Atmaca, N.; Atmaca, H. T.; Kanicic, A.; Anteplioglu, T. Protective effect of resveratrol on sodium fluoride-induced oxidative stress, hepatotoxicity and neurotoxicity in rats. Food Chem. Toxicol. 2014, 70, 191-197.
Dichiarazioni di rischio (UE): H301-H315-H319
Toxic if swallowed. Causes skin irritation. Causes serious eye irritation.
Dichiarazioni precauzionali: P280a-P301+P310a-P305+P351+P338-P321-P405-P501a
Wear protective gloves and eye/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.