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5965-83-3 - 5-Sulfosalicylic acid dihydrate, 98% - 2-Hydroxy-5-sulfobenzoic acid dihydrate - A13461 - Alfa Aesar

A13461 5-Sulfosalicylic acid dihydrate, 98%

Codice CAS
5965-83-3
Sinonimi
2-Hydroxy-5-sulfobenzoic acid dihydrate

Dimensioni Prezzo ($) Quantità Disponibilità
100g 22,34
250g 35,43
1000g 95,40
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5-Sulfosalicylic acid dihydrate, 98%

MDL
MFCD00007508
EINECS
202-555-6

Proprietà chimiche

Formula
C7H6O6SH•2H2O
Peso formula
254.22 (218.19anhy)
Punto di fusione
103-112°
Sensibilità
Light Sensitive
Solubilità
Soluble in water

Applicazioni

5-Sulfosalicylic acid dihydrate may be employed for the quantification of doxorubicin derived from PEGylated liposomal doxorubicin (Doxil) and its major metabolite in human plasma by HPLC. It may be used in the preparation of poly[[tris(di-2-pyridylamine)tris([?]-5-sulfonatosalicylato)tricopper(II)] trihydrate]. Also used as an intermediate synthesis of bulk drugs, surfactant and additive for lubricating grease.

Note

Light Sensitive, store in dark. Store in cool, dry place in tightly closed container. Store away from strong bases and oxidizing agent.

Letteratura

David L Chin et. al. Rapid determination of PEGylated liposomal doxorubicin and its major metabolite in human plasma by ultraviolet-visible high-performance liquid chromatography. Journal of Chromatography B. 2002, 779(2), 259-269.

Fan S-R; and Zhu L-G. Poly [[tris (di-2-pyridylamine) tris (-5-sulfonatosalicylato) tricopper (II)] trihydrate]. Acta Crystallogr. Sect. E Struct. Rep. Online, 2004, 61 (1), m174-m176.

Deproteinization reagent: J. Chromat., 74, 255 (1973); 570, 285 (1991). Spray reagent for detection of sugars on TLC: J. Chromat., 315, 401 (1985).

Acid catalyst, alternative to tosic acid in certain esterification and acetalization reactions: Org. Synth. Coll., 1, 246 (1941); J. Am. Chem. Soc., 76, 743 (1954); 80, 6613 (1958); J. Org. Chem., 28, 2425 (1963).

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H314-H318-H302

Causes severe skin burns and eye damage. Causes serious eye damage. Harmful if swallowed.

Dichiarazioni precauzionali: P260-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310-P301+P312-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or doctor/physician. Call a POISON CENTER or doctor/physician if you feel unwell. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,8964
Beilstein
650741
Classe di rischio
8
Gruppo di imballaggio
III
Codice tariffe armonizzato
2918.29
TSCA
Yes
RTECS
VO6500000

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