Accetto Utilizziamo cookies per migliorare il nostro servizio e realizzare statistiche. Questa funzione puó essere disattivata cambiando la configurazione del browser. Continuando a navigare senza modificare questi parametri, consideriamo che l’uso di cookies sia accettato
Ethyl trifluoroacetoacetate is used as an intermediate in synthetic chemistry. It is also used as an intermediate for agro chemicals and pharmaceuticals. Further, it is used in the preparation of fluorinated 2-thiouracil analogs as antithyroid agents.
For discussion of factors influencing O- vs C-alkylation, see: J. Chem. Soc., Chem. Commun., 83 (1989).
Mogilaiah, K.; Rao, A. N.; Rao, P. K. ZrOCl2.8H2O catalyzed solvent-free Friedlander synthesis of 1,8-naphthyridines. Indian J. Chem. 2015, 54 (10), 1280-1282.
Lensen, N.; Marais, J.; Brigaud, T. Straightforward Synthesis of Novel Enantiopure alpha-Trifluoromethylated Azetidine 2-Carboxylic Acid and Homoserines. Org. Lett. 2015, 17 (2), 342-345.
Dichiarazioni di rischio (UE): H226-H302
Flammable liquid and vapour. Harmful if swallowed.
Dichiarazioni precauzionali: P210-P280a-P240-P241-P303+P361+P353-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Wear protective gloves and eye/face protection. Ground/bond container and receiving equipment. Use explosion-proof electrical/ventilating/lighting/ equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. Dispose of contents/container in accordance with local/regional/national/international regulations.