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6192-52-5 - p-Toluenesulfonic acid monohydrate, 98% - PTSA - Tosic acid monohydrate - A14119 - Alfa Aesar

A14119 p-Toluenesulfonic acid monohydrate, 98%

Codice CAS
6192-52-5
Sinonimi
PTSA
Tosic acid monohydrate

Dimensioni Prezzo ($) Quantità Disponibilità
100g 16,10
500g 42,60
5000g 181,00
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p-Toluenesulfonic acid monohydrate, 98%

MDL
MFCD00142137
EINECS
203-180-0

Proprietà chimiche

Formula
C7H8O3S•H2O
Peso formula
190.22 (172.20anhy)
Punto di fusione
103-106°(anhy)
Punto di ebollizione
140°/20mm
Punto di infiammabilità
150°(302°F)
Densità
1.24
Sensibilità
Hygroscopic

Applicazioni

p-Toluenesulfonic acid monohydrate is used as a catalyst in the synthesis of resveratrol, in oxane derivatives as an antimalarial agent, as substituted piperidine and unsymmetrical benzyl. It acts as a catalyst in the preparation of 1,3,5-trisubstituted pyrazoles derivatives, selenated ketene dithioacetals, triazoloquinazolinone and benzimidazoquinazolinone derivatives. It also serves as an intermediate in the esterification and in reductive amination reactions.

Note

Hygroscopic. Incompatible with strong oxidizing agents and strong bases.

Letteratura

For examples of the numerous applications as an organic-soluble acid catalyst, see:

Esterifications: Org. Synth. Coll., 3, 146, 203, 610 (1955); 9, 722 (1998). Enamine formation: Org. Synth. Coll., 5, 277, 808 (1973); 6, 520 (1988). Protection of alcohols as their THP ethers: Org. Synth. Coll., 7, 334 (1990). Formation acetals: Org. Synth. Coll., 6, 567 (1988); 8, 155 (1993); 9, 251, 717 (1998), and oxazolidines: Org. Synth. Coll., 9, 300 (1998).

Adsorbed on silica gel, has been used for the dehydration of sec- and tert-alcohols to alkenes in good yield: Synthesis, 1159 (1985).

See also Pyridinium p-toluenesulfonate, A15708.

Jauhar, R. M.; Kalainathan, S.; Murugakoothan, P. Three dimensional organic framework of 2-amino 4, 6 dimethoxypyrimidine p-toluenesulfonic acid monohydrate: synthesis, single crystal growth and its properties. J. Cryst. Growth 2015, 424, 3716-3722.

Davarpanah, M.; Ahmadpour, A.; Rohani-Bastami, T.; Dabir, H. Synthesis and application of diethanolamine-functionalized polystyrene as a new sorbent for the removal of p-toluenesulfonic acid from aqueous solution. J. Ind. Eng. Chem. 2015, 30, 3716-3722.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H303-H314-H319-H335

May be harmful if swallowed. Causes severe skin burns and eye damage. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,9533
Beilstein
3568023
Classe di rischio
8
Gruppo di imballaggio
III
Codice tariffe armonizzato
2904.10
TSCA
Yes
RTECS
DB7164000

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