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2-Butyne-1,4-diol is used as a precursor to prepare 1,4-butanediol, 2-butene-1,4-diol and mucochloric acid. It is also used in textile additives, corrosion inhibitors, plasticizers, synthetic resins and polyurethanes. It is an important raw material of vitamin B6. Further, it is used for brightening, preserving and inhibiting nickel plating. In addition, it is used in biological studies for nematocidal activity.
Undergoes an interesting trans-addition reaction with Grignard reagents: Chem. Lett., 765 (1984):
Kotha, S.; Ali, R. Diversity-oriented approach to intricate bis-armed spirocycles involving a two directional [2+ 2+ 2] co-trimerization and the [4+ 2] cycloaddition reaction as key steps. Tetrahedron Lett. 2015, 56 (17), 2172-2175.
Elchaninov, M. M.; Pyatnitsyna, E. V.; Elchaninov, I. M. Step mechanism of 1-butanol formation in the course of liquid-phase catalytic hydrogenation of 2-butyne-1, 4-diol. Russ. J. Appl. Chem. 2015, 88 (4), 585-589.
Dichiarazioni di rischio (UE): H301-H312-H331-H314-H317-H373
Toxic if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes severe skin burns and eye damage. May cause an allergic skin reaction. May cause damage to organs through prolonged or repeated exposure.
Dichiarazioni precauzionali: P260u-P201-P280g-P304+P340-P405-P501a
Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.