A14604 4,4'-Dimethoxybenzhydrol, 98+%
SDS
| Stock No. | Dimensioni | Prezzo ($) | Quantità | Disponibilità |
|---|---|---|---|---|
| A14604-09 | 10g | 62,00 |
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| A14604-18 | 50g | 218,00 |
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4,4'-Dimethoxybenzhydrol, 98+%
Proprietà chimiche
Applicazioni
4,4?-Dimethoxybenzhydrol was used to study the kinetics and mechanism of oxidation of substituted benzhydrols to corresponding benzophenones in the presence of Hg(OAc)2 by N-bromosuccinimide. It is useful in the protection of glutamine and asparagine residues in peptide synthesis, reagent for the N-protection of amides.
Note
Letteratura
B. L. Hiran; R. K. Malkani; N. Rathore. Kinetics and mechanism of oxidation of some substituted benzhydrols by N-bromosuccinimide. Kinetics and Catalysis. 1992, 46 (3), 334-339.
C Henneuse; T Boxus; L Tesolin; G Pantano. One-Step Hydroxy Substitution of 4, 4'-Dimethoxybenzhydrol with Amides, Lactams, Carbamates, Ureas and Anilines. Synthesis. 1996, 1996 (4), 495-501.
Reagent for the N-protection of amides, useful in the protection of glutamine and asparagine residues in peptide synthesis. Substitution of the OH group with amide and a variety of other N functionalities occurs readily in AcOH with H2SO4 catalysis: Chem. Ber., 103, 2041 (1970); Synthesis, 495 (1996). Deprotection occurs in TFA.
