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A14720 8-Hydroxyquinoline, 99%

Codice CAS
148-24-3
Sinonimi
8-Quinolinol
Oxine

Stock No. Dimensioni Prezzo ($) Quantità Disponibilità
A14720-22 100g 31,30
A14720-36 500g 109,00
A14720-0E 2500g 424,00
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8-Hydroxyquinoline, 99%

MDL
MFCD00006807
EINECS
205-711-1

Proprietà chimiche

Formula
C9H7NO
Peso formula
145.16
Punto di fusione
72-76°
Punto di ebollizione
267°
Storage & Sensitivity
Light Sensitive. Ambient temperatures.
Solubilità
Almost insoluble in water and diethyl ether. Highly soluble in ethanol, acetone, chloroform, and benzene.Soluble in acetic acid, ethanol, acetone, chloroform, benzene and aqueous mineral acids. Insoluble in water and diethylether.

Applicazioni

8-Hydroxyquinoline is used as an antiseptic and disinfectant. Its alcoholic solution is used in liquid bandages. It is used to prepare tris(8-hydroxyquinolinato)aluminum, which finds application as a component of organic light-emitting diodes (OLED's). It is also used as a reagent and as a stabilizer of hydrogen peroxide in a rocket fuel oxidizer. It is used as a chelating agent and used as a carrier for radio-indium for diagnostic purposes. Its halogenated derivatives are used as anti-infective agents and oral antiamebics.

Note

Light sensitive. Incompatible with oxidizing agents.

Letteratura

Chelating ligand.

Thinnes, C. C.; Tumber, A.; Yapp, C.; Scozzafava, G.; Yeh, T.; Chan, M. C.; Tran, T. A.; Hsu. K.; Tarhonskaya, H.; Walport, L. J.; Wilkins, S. E.; Martinez, E. D.; Müller, S.; Pugh, C. W.; Ratcliffe, P. J.; Brennan, P. E.; Kawamura, A.; Schofield, C. J. Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases. Chem. Commun. 2015, 51 (84), 15458-15461.

Liang, S. H.; Southon, A. G.; Fraser, B. H.; Krause-Heuer, A. M.; Zhang, B.; Shoup, T. M.; Lewis, R.; Volitakis, I.; Han, Y.; Greguric, I.; Bush, A. I.; Vasdev, N. Novel fluorinated 8-hydroxyquinoline based metal ionophores for exploring the metal hypothesis of Alzheimer’s disease. ACS Med. Chem. Lett. 2015, 6 (9), 1025-1029.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H341

Harmful if swallowed. Suspected of causing genetic defects.

Dichiarazioni precauzionali: P201-P280-P301+P312a-P308+P313-P405-P501a

Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Call a POISON CENTER/doctor if you feel unwell. IF exposed or concerned: Get medical advice/attention. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,4843
Beilstein
114512
Codice tariffe armonizzato
2933.49
TSCA
Yes
RTECS
VC4200000

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