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148-24-3 - 8-Hydroxyquinoline, 99% - 8-Quinolinol - Oxine - A14720 - Alfa Aesar

A14720 8-Hydroxyquinoline, 99%

Codice CAS
148-24-3
Sinonimi
8-Quinolinol
Oxine

Dimensioni Prezzo ($) Quantità Disponibilità
100g 30,69
500g 93,60
2500g 420,24
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8-Hydroxyquinoline, 99%

MDL
MFCD00006807
EINECS
205-711-1

Proprietà chimiche

Formula
C9H7NO
Peso formula
145.16
Punto di fusione
72-76°
Punto di ebollizione
267°
Sensibilità
Light Sensitive
Solubilità
Almost insoluble in water and diethyl ether. Highly soluble in ethanol, acetone, chloroform, and benzene.Soluble in acetic acid, ethanol, acetone, chloroform, benzene and aqueous mineral acids. Insoluble in water and diethylether.

Applicazioni

8-Hydroxyquinoline is used as an antiseptic and disinfectant. Its alcoholic solution is used in liquid bandages. It is used to prepare tris(8-hydroxyquinolinato)aluminum, which finds application as a component of organic light-emitting diodes (OLED's). It is also used as a reagent and as a stabilizer of hydrogen peroxide in a rocket fuel oxidizer. It is used as a chelating agent and used as a carrier for radio-indium for diagnostic purposes. Its halogenated derivatives are used as anti-infective agents and oral antiamebics.

Note

Light sensitive. Incompatible with oxidizing agents.

Letteratura

Chelating ligand.

Thinnes, C. C.; Tumber, A.; Yapp, C.; Scozzafava, G.; Yeh, T.; Chan, M. C.; Tran, T. A.; Hsu. K.; Tarhonskaya, H.; Walport, L. J.; Wilkins, S. E.; Martinez, E. D.; Müller, S.; Pugh, C. W.; Ratcliffe, P. J.; Brennan, P. E.; Kawamura, A.; Schofield, C. J. Betti reaction enables efficient synthesis of 8-hydroxyquinoline inhibitors of 2-oxoglutarate oxygenases. Chem. Commun. 2015, 51 (84), 15458-15461.

Liang, S. H.; Southon, A. G.; Fraser, B. H.; Krause-Heuer, A. M.; Zhang, B.; Shoup, T. M.; Lewis, R.; Volitakis, I.; Han, Y.; Greguric, I.; Bush, A. I.; Vasdev, N. Novel fluorinated 8-hydroxyquinoline based metal ionophores for exploring the metal hypothesis of Alzheimer’s disease. ACS Med. Chem. Lett. 2015, 6 (9), 1025-1029.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H341-H302

Suspected of causing genetic defects. Harmful if swallowed.

Dichiarazioni precauzionali: P201-P281-P264-P270-P202-P301+P312-P308+P313-P330-P405-P501a

Obtain special instructions before use. Use personal protective equipment as required. Wash thoroughly after handling. Do not eat, drink or smoke when using this product. Do not handle until all safety precautions have been read and understood. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. IF exposed or concerned: Get medical advice/attention. Rinse mouth. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,4843
Beilstein
114512
Codice tariffe armonizzato
2933.49
TSCA
Yes
RTECS
VC4200000

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