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Dichloroacetic acid salts are used as drugs due to its inhibition of the enzyme pyruvate dehydrogenase kinase. It is also employed to stem the production of lactic acid to treat lactic acidosis. It is clinically essential in children to treat lactic acidosis.
Moderately strong acid which has been recommended for the catalysis of mixed acetal formation by reaction of alcohols with Ethyl vinyl ether, A15691 . Has also been used as an acid catalyst and deprotecting agent in various other applications including peptide synthesis.
Ding, Y.; Zhu, J.; Ji, D.; Cao, Y.; Ling, X.; Chen, W. Enhancing adsorption efficiency of dichloroacetic acid onto mesoporous carbons: Procedure optimization, mechanism and characterization. J. Colloid Interface Sci. 2015, 452, 134-140.
Scialdone, O.; Galia, A.; Sabatino, S.; Mira, D.; Amatore, C. Electrochemical Conversion of Dichloroacetic Acid to Chloroacetic Acid in a Microfluidic Stack and in a Series of Microfluidic Reactors. Chem. Electro. Chem. 2015, 2 (5), 684-690.
Dichiarazioni di rischio (UE): H314-H351
Causes severe skin burns and eye damage. Suspected of causing cancer.
Dichiarazioni precauzionali: P260u-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.