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Benzyl isothiocyanate is used in a synthesis of 2-phenylpyrimidine-4-thiones from Benzoylacetonitrile. Benzyl isothiocyanate has been used in the preparation of S-(N-benzylthiocarbamoyl)-L-glutathione and S-(N-benzylthiocarbamoyl)-L-cysteine.
I.M. Bruggeman.; J.H.M. Temmink.; P.J. van Bladeren. Glutathione- and cysteine-mediated cytotoxicity of allyl and benzyl isothiocyanate. Toxicology and Applied Pharmacology. 1986, 83, (2), 349-359.
Chung-Shih Tang. Benzyl isothiocyanate of papaya fruit . Phytochemistry. 1971, 10, (1), 117-121.
Used in a synthesis of 2-phenylpyrimidine-4-thiones from Benzoylacetonitrile, A14473: Synthesis, 775 (1989).
Dichiarazioni di rischio (UE): H302-H312-H331-H314-H318-H334-H317-H351
Harmful if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage. May cause allergy or asthma symptoms or breathing difficulties if inhaled. May cause an allergic skin reaction. Suspected of causing cancer.
Dichiarazioni precauzionali: P260u-P284-P303+P361+P353-P305+P351+P338-P405-P501a
Do not breathe dusts or mists. Wear respiratory protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.