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4-Bromoaniline is used as a precursor in the production of azo dyes and dihydroquinazolines. It is also used as carbon and nitrogen supplement in the culture medium of Moraxella sp. strain G. Further, it is employed in the preparation of para-bromobiphenyl through Gomberg-Bachmann reaction. In addition to this, it is used as a building block in the preparation or pharmaceutical and organic compounds.
Gao, W. Synthesis and Structure Analysis of N-diphenylphosphoryl-4-bromoaniline. Mol. Cryst. Liq. Cryst. 2015, 609 (1), 155-160.
Štrukil, V.; Gracin, D.; Magdysyuk, O. V.; Dinnebier, R. E.; Frišči?, T. Trapping Reactive Intermediates by Mechanochemistry: Elusive Aryl N-Thiocarbamoylbenzotriazoles as Bench-Stable Reagents. Angew. Chem. Int. Ed. 2015, 54 (29), 8440-8443.
Dichiarazioni di rischio (UE): H302-H311-H332-H315-H319-H373
Harmful if swallowed. Toxic in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause damage to organs through prolonged or repeated exposure.
Dichiarazioni precauzionali: P260-P201-P280h-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves/clothing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.