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It is used in the production of pharma ingredients. It is a reagent in the synthesis of S-Methyl-N,N-diethylthiocarbamate Sulfoxide, which is an oxygenated metabolite of Disulfiram (Antabuse) that is capable of in vitro inactivation of liver mitochondrial aldehyde dehydrogenase.
A. Segal, et al. Formation of 6-dimethylcarbamyloxy-dGuo, 6-dimethylamino-dGuo and 4-dimethylamino-dThd following in vitro reaction of dimethylcarbamyl chloride with calf thymus DNA and 6-diethylcarbamyloxy-dGuo following in vitro reaction of diethylcarbamyl chloride with calf thymus DNA.Chem. Biol. Interact.,1982,40(2), 209-231.
S. Kushner, et al. Experimental chemotherapy of filariasis. v. the preparation of derivatives of piperazine.J. Org. Chem.,1948,13(1), 144-153.
Dichiarazioni di rischio (UE): H227-H302-H332-H315-H319-H351-H335
Combustible liquid. Harmful if swallowed. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. Suspected of causing cancer. May cause respiratory irritation.
Dichiarazioni precauzionali: P210u-P201-P261-P305+P351+P338-P405-P501a
Obtain special instructions before use. Avoid breathing dust/fume/gas/mist/vapours/spray. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.