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1,3-Dichloro-2-propanol biotransformation to epichlorohydrin by the whole cells of recombinant Escherichia coli via resin-based in situ product removal has been investigated. It is used in the synthesis of glycerol, in the production of plastics and textiles and in the synthesis of pharmaceuticals. Also used as a solvent and as a cement for celluloid. It is also present in some foods, e.g. soy sauce, soup spices and instant soups, from hydrolization of proteins.
Shu-Ping Zou; Er-Hong Du; Zhong-Ce Hu; Yu-Guo Zheng. Enhanced biotransformation of 1,3-dichloro-2-propanol to epichlorohydrin via resin-based in situ product removal process. Biotechnology Letters. 2013, 35, (6),937-942
T.Nakamura; T.Nagasawa; F.Yu; I.Watanabe; H.Yamada. Resolution and some properties of enzymes involved in enantioselective transformation of 1,3-dichloro-2-propanol to (R)-3-chloro-1,2-propanediol by Corynebacterium sp. strain N-1074. Journal of Bacteriology. 1992, 174, (23),7613-7619
Dichiarazioni di rischio (UE): H227-H301-H312-H350
Combustible liquid. Toxic if swallowed. Harmful in contact with skin. May cause cancer.
Dichiarazioni precauzionali: P210u-P201-P280-P301+P310a-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Obtain special instructions before use. Wear protective gloves/protective clothing/eye protection/face protection. IF SWALLOWED: Immediately call a POISON CENTER/doctor Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.