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6119-70-6 - Quinine hemisulfate monohydrate, 99% - Quinine sulfate (2:1) (salt) dihydrate - Quinine sulfate dihydrate - A17036 - Alfa Aesar

A17036 Quinine hemisulfate monohydrate, 99%

Codice CAS
6119-70-6
Sinonimi
Quinine sulfate (2:1) (salt) dihydrate
Quinine sulfate dihydrate

Dimensioni Prezzo ($) Quantità Disponibilità
10g 34,30
50g 85,18
250g 291,20
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Quinine hemisulfate monohydrate, 99%

MDL
MFCD00150792
EINECS
212-359-2

Proprietà chimiche

Formula
C20H24N2O2•0.5H2SO4•H2O
Peso formula
391.47 (373.46anhy)
Punto di fusione
217-218° dec.
Sensibilità
Light Sensitive
Solubilità
Soluble in a mixture of chloroform and absolute alcohol (2:1).

Applicazioni

Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.

Note

Light sensitive. Incompatible with strong oxidizing agents, alkalis, ammonia, strong bases and iodine.

Letteratura

Krzeszewski, M.; Gryko, D. T. x-Shaped Bis (areno)-1, 4-dihydropyrrolo [3, 2-b] pyrroles Generated by Oxidative Aromatic Coupling. J. Org. Chem. 2015, 80 (5), 2893-2899.

Janiga, A.; Krzeszewski, M.; Gryko, D. T. Diindolo [2, 3-b: 2', 3'-f] pyrrolo [3, 2-b] pyrroles as Electron-Rich, Ladder-Type Fluorophores: Synthesis and Optical Properties. Chem. Asian J. 2015, 10 (1), 212-218.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H302-H312-H332-H315-H319-H335

Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P301+P312-P312-P363-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,8061
Beilstein
6113937
Codice tariffe armonizzato
2939.20
TSCA
Yes
RTECS
VA8440000

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