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Quinine hemisulfate monohydrate plays a major role in potassium channel blockers. It is also used as an antimalarial, anticholinergic, antihypertensive and a hypoglycemic agent. It inhibits mitochondrial ATP-regulated potassium channel. It is also used to study the metabolism of biocrystalized heme, hemozoin, in malarial parasites and to study the toxicity of heme (FP)-complexes.
Krzeszewski, M.; Gryko, D. T. x-Shaped Bis (areno)-1, 4-dihydropyrrolo [3, 2-b] pyrroles Generated by Oxidative Aromatic Coupling. J. Org. Chem. 2015, 80 (5), 2893-2899.
Janiga, A.; Krzeszewski, M.; Gryko, D. T. Diindolo [2, 3-b: 2', 3'-f] pyrrolo [3, 2-b] pyrroles as Electron-Rich, Ladder-Type Fluorophores: Synthesis and Optical Properties. Chem. Asian J. 2015, 10 (1), 212-218.
Dichiarazioni di rischio (UE): H302-H312-H332-H315-H319-H335
Harmful if swallowed. Harmful in contact with skin. Harmful if inhaled. Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.