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10523-68-9 - 2-Adamantanamine hydrochloride, 98+% - 2-Aminoadamantane hydrochloride - A17140 - Alfa Aesar

A17140 2-Adamantanamine hydrochloride, 98+%

Codice CAS
10523-68-9
Sinonimi
2-Aminoadamantane hydrochloride

Dimensioni Prezzo ($) Quantità Disponibilità
1g 25,90
5g 76,10
25g 281,00
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2-Adamantanamine hydrochloride, 98+%

MDL
MFCD00074743
EINECS
234-074-2

Proprietà chimiche

Formula
C10H17N•HCl
Peso formula
187.71
Punto di fusione
>300°
Solubilità
Soluble in water.

Applicazioni

2-Adamantylamine hydrochloride was used to prepare 2-adamantylamide of 2?-(carboxymethoxime)-olivomycin I. The HPLC assay of 2-adamantylamine hydrochloride after pre-column derivatization with 4-fluoro-7-nitro-2,1,3-benzoxadiazole has been studied. It is also used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from oxidizing agents.

Letteratura

JS Scott.; J deSchoolmeester.; E Kilgour. Novel Acidic 11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) Inhibitor with Reduced Acyl Glucuronide Liability: The Discovery of 4-[4-(2-Adamantylcarbamoyl)-5-tert-butyl-pyrazol-1-yl]benzoic Acid (AZD8329). J. Med. Chem.201255 (22), 10136-10147.

SW Kwon.; SK Kang.; JH Lee.; JH Bok.; CH Kim. Synthesis and 11β hydroxysteroid dehydrogenase 1 inhibition of thiazolidine derivatives with an adamantyl group. Bioorganic & Medicinal Chemistry Letters. 201121 (1), 435-439.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
4297901
Codice tariffe armonizzato
2921.30
TSCA
No
RTECS
AU4375100

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