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832-53-1 - 2,3,4,5,6-Pentafluorobenzenesulfonyl chloride, 98+% - A17676 - Alfa Aesar

A17676 2,3,4,5,6-Pentafluorobenzenesulfonyl chloride, 98+%

Codice CAS
832-53-1
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 21,00
5g 59,60
25g 231,00
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2,3,4,5,6-Pentafluorobenzenesulfonyl chloride, 98+%

MDL
MFCD00007427
EINECS
212-620-0

Proprietà chimiche

Formula
C6ClF5O2S
Peso formula
266.57
Punto di ebollizione
210-211°
Punto di infiammabilità
90°(194°F)
Densità
1.796
Indice di rifrazione
1.4790
Sensibilità
Moisture Sensitive
Solubilità
Soluble in water (reacts slowly).

Applicazioni

Pentafluorobenzenesulfonyl chloride is used as derivatizing reagent for simultaneous determination of fluoxetine and p-trifluoromethylphenol, an O-dealkylated metabolite of fluoxetine in human liver microsomes. It is also used for electrophore labeling of small tyrosyl peptides for their analysis by gas chromatography with electron-capture detection. It is also employed as derivatizing reagent for amphetamine in determination of amphetamine in human plasma samples using gas chromatography with electron-capture detection.

Note

Moisture Sensitive. Store away from oxidizing agents, active metals and bases, water/moisture. Keep the container tightly closed in a cool, dry place. Store under inert gas.

Letteratura

Zhao-Qian Liu.; Zhi-Rong Tan.; Dan Wang.; Song-Lin Huang.; Lian-Sheng Wang.; Hong-Hao Zhou. Simultaneous determination of fluoxetine and its metabolite p-trifluoromethylphenol in human liver microsomes using a gas chromatographic-electron-capture detection procedure.J Chromatogr B Analyt Technol Biomed Life Sci.2002,769(2), 305-311.

A Sentissi.; M Joppich.; K O'Connell.; A Nazareth.; R W Giese. Pentafluorobenzenesulfonyl chloride: a new electrophoric derivatizing reagent with application to tyrosyl peptide determination by gas chromatography with electron capture detection.Anal Chem.1984,56(13), 2512-2517.

S J Asghar.; G B Baker.; G A Rauw.; P H Silverstone. A rapid method of determining amphetamine in plasma samples using pentafluorobenzenesulfonyl chloride and electron-capture gas chromatography.J Pharmacol Toxicol Methods.2001,46(2), 111-115.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H227-H314-H318

Combustible liquid. Causes severe skin burns and eye damage. Causes serious eye damage.

Dichiarazioni precauzionali: P210u-P260u-P303+P361+P353-P305+P351+P338-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Do not breathe dusts or mists. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
2142325
Classe di rischio
8
Gruppo di imballaggio
II
Codice tariffe armonizzato
2904.99
TSCA
No

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