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111-30-8 - Glutaraldehyde, 25% aq. soln. - Glutaric dialdehyde - Pentanedial - A17876 - Alfa Aesar

A17876 Glutaraldehyde, 25% aq. soln.

Codice CAS
111-30-8
Sinonimi
Glutaric dialdehyde
Pentanedial

Dimensioni Prezzo ($) Quantità Disponibilità
100ml 19,20
500ml 38,50
2500ml 94,70
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Glutaraldehyde, 25% aq. soln.

MDL
MFCD00007025
EINECS
203-856-5

Proprietà chimiche

Formula
C5H8O2
Peso formula
100.12
Densità
1.062
Indice di rifrazione
1.3730
Solubilità
Miscible with water, ethanol, benzene, ether, acetone, dichloromethane, ethylacetate, isopropanol, n-hexane and toluene.

Applicazioni

Glutaraldehyde is used for cross-linking proteins and polyhydroxy materials. Also used as a fixative for tissues and as an amine-reactive homobifunctional crosslinker. It is also used in coupling reaction of biotin hydrazides to nucleic acids which is useful for conjugating fluorescent hydrazides and hydroxylamines to DNA and for stabilization ofproteins on agarose beads,activation of polystyrene and glass, for immobilization of antibodies and antigens.

Note

Heat and air sensitive. Incompatible with strong acids, strong bases and strong oxidizing agents.

Letteratura

For use in the Robinson synthesis of pseudopelletierine, see Acetone-1,3-dicarboxyl­ic acid, A13742.

Reaction with (R)-(-)-2-Phenyl­glycinol, A19030, gives an intermediate for asymmetric synthesis of alkaloids: Org. Synth. Coll., 9, 176 (1998).

Cho, K. L.; Hill, A. J.; Caruso, F.; Kentish, S. E. Chlorine Resistant Glutaraldehyde Crosslinked Polyelectrolyte Multilayer Membranes for Desalination. Adv. Mater. 2015, 27 (17), 2791-2796.

Vikram, A.; Bomberger, J. M.; Bibby, K. J. Efflux as a Glutaraldehyde Resistance Mechanism in Pseudomonas fluorescens and Pseudomonas aeruginosa Biofilms. Antimicrob. Agents Chemother. 2015, 59 (6), 3433-3440.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H331-H302-H317-H334-H314-H400

Toxic if inhaled. Harmful if swallowed. May cause an allergic skin reaction. May cause allergy or asthma symptoms or breathing difficulties if inhaled. Causes severe skin burns and eye damage. Very toxic to aquatic life.

Dichiarazioni precauzionali: P260-P285-P261-P273-P280-P303+P361+P353-P305+P351+P338-P301+P330+P331-P405-P501a

Do not breathe dust/fume/gas/mist/vapours/spray. In case of inadequate ventilation wear respiratory protection. Avoid breathing dust/fume/gas/mist/vapours/spray. Avoid release to the environment. Wear protective gloves/protective clothing/eye protection/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,4472
Beilstein
605390
Classe di rischio
8
Gruppo di imballaggio
III
Codice tariffe armonizzato
2912.19
TSCA
Yes
RTECS
MA2450000

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