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206658-89-1 - 3-Aminobenzeneboronic acid monohydrate, 97% - 3-Aminophenylboronic acid monohydrate - A18189 - Alfa Aesar

A18189 3-Aminobenzeneboronic acid monohydrate, 97%

Codice CAS
206658-89-1
Sinonimi
3-Aminophenylboronic acid monohydrate

Dimensioni Prezzo ($) Quantità Disponibilità
1g 54,60
5g 194,00
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3-Aminobenzeneboronic acid monohydrate, 97%

MDL
MFCD00149554
EINECS
250-189-0

Proprietà chimiche

Formula
C6H8BNO2•H2O
Peso formula
154.96 (136.95anhy)
Punto di fusione
93-97°
Sensibilità
Air & Moisture Sensitive
Solubilità
Soluble in DMSO and methanol.

Applicazioni

It is employed as a reagent in the preparation of Suzuki-Miyaura cross-coupling, used for Gram-positive ant virulence drugs and inhibitors of Streptococcus agalactiae Stk1, regioisomer of Zaleplon (a sedative), amphiphilic random glycopolymer, which self-assemble to form nanoparticles, with potential as a glucose-sensitive matrix, chemomechanical polymer that expands and contracts in blood plasma with high glucose selectivity. Aminophenylboronic Acid is also used as a reagent in the preparation of nonbenzodiazepine hypnotic agents.

Note

Air & Moisture Sensitive. Store away from oxidizing agents, air, water/moisture. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Letteratura

Gregory D. Cuny.; Maxime Robin.; Natalia P. Ulyanova.; Debasis Patnaik.; Valerie Pique.; Gilles Casano.; Ji-Feng Liu.; Xiangjie Lin.; Jun Xian.; Marcie A. Glicksman.; Ross L. Stein.; Jonathan M.G. Higgins. Structure-activity relationship study of acridine analogs as haspin and DYRK2 kinase inhibitors.Bioorg Med Chem Lett.2010,20(12), 3491-3494.

Xingju Jin.; Xinge Zhang.; Zhongming Wu.; Dayong Teng.; Xuejiao Zhang.; Yanxia Wang.; Zhen Wang.; Chaoxing Li. Amphiphilic random glycopolymer based on phenylboronic acid: synthesis, characterization, and potential as glucose-sensitive matrix.Biomacromolecules.2009,10(6), 1337-1345.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319

Causes skin irritation. Causes serious eye irritation.

Dichiarazioni precauzionali: P260u-P201-P280a-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P310a-P405-P501a

Obtain special instructions before use. Wear protective gloves and eye/face protection. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
2936342
Codice tariffe armonizzato
2931.90
TSCA
No

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