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42348-86-7 - 5-Chloro-1-indanone, 99% - A18308 - Alfa Aesar

A18308 5-Chloro-1-indanone, 99%

Codice CAS
42348-86-7
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 42,30
5g 159,65
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5-Chloro-1-indanone, 99%

MDL
MFCD00041456

Proprietà chimiche

Formula
C9H7ClO
Peso formula
166.61
Punto di fusione
92-96°
Punto di ebollizione
124-125°/3mm
Solubilità
Insoluble in water.

Applicazioni

5-Chloro-1-indanone may be used as starting reagent for the preparation of 5-chloro-2-methoxycarbonyl-1-indanone. It may also be used for the preparation of important biomedical compounds such as anticonvulsants, anticholinergics and diarylsulfonylureas, having potential activity against solid tumors. It participates in the Irie?s synthesis of substituted pyridines.

Note

Stable under recommended storage conditions. Incompatible with oxidizing agents.

Letteratura

Mark T. DuPriest; Charles L.Schmidt; Daniel Kuzmich; Stanly B.Williams. A facile synthesis of 7-halo-5H-indeno[1,2-b]pyridines and -pyridin-5-ones. J. Org. Chem. 1986, 51,(11), 2021-2023.

 

Tomas Pena Ruiz; Manuel Fernandez Gomez; Juan Jesus Lopez Gonzalez; Anna E.Koziol. Weak hydrogen-, halogen- and stacking π?π bonding in crystalline 5-chloro-1-indanone. An analysis by using X-ray diffraction, vibrational spectroscopy and theoretical methods. Chemical Physics. 2006, 320,(2-3), 164-180.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
1448000
Codice tariffe armonizzato
2914.70
TSCA
Yes

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