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Ethyl acetimidate hydrochloride was used in preparation of amidinated carbonic anhydrase via chemical modification of human erythrocyte carbonic anhydrase. It was also used in synthesis of methyl 2-methyl-2-thiazoline-4-carboxylate hydrochloride.
P L Whitney; P O Nyman; B G Malmström. Inhibition and chemical modifications of human erythrocyte carbonic anhydrase B. Journal of Biological Chemistry. 1967, 242 (18), 4212-4220.
Smith HA: Goring G. 2-Methyl-2-thiazoline-4-carboxylic acid: formation from N-acetylcysteine and hydrolysis. J. Org. Chem. 1961, 26 (3), 820-23.
Dichiarazioni di rischio (UE): H315-H319-H335
Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.
Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a
Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.