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Acetylenedicarboxylic acid is employed in the preparation of dimethyl acetylenedicarboxylate and potassium hydrogenacetylenedicarboxylate. It is also used as a laboratory reagent. Further, it is used as a precursor in organic synthesis and also serves as a pharmaceutical intermediate.
Fung, E.; Chua, K.; Ganz, T.; Nemeth, E.; Ruchala, P. Thiol-derivatized minihepcidins retain biological activity. Bioorg. Med. Chem. Lett. 2015, 25 (4), 763-766.
Demetrowitsch, T. J.; Petersen, B.; Keppler, J. K.; Koch, A.; Schreiber, S.; Laudes, M.; Schwarz, K. Validation of a two-step quality control approach for a large-scale human urine metabolomic study conducted in seven experimental batches with LC/QTOF-MS. Bioanalysis 2015, 7 (1), 103-112.
Dichiarazioni di rischio (UE): H300-H310-H330-H314-H318
Fatal if swallowed. Fatal in contact with skin. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Dichiarazioni precauzionali: P301+P310a-P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501a
IF SWALLOWED: Immediately call a POISON CENTER/doctor IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.