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It is active against a wide range of bacteria, but is mainly employed for its actions against Mycobacterium leprae, being used as part of multidrug regimens in the treatment of all forms of leprosy. It is a second-line medication for the treatment and prevention of Pneumocystis pneumonia and for the prevention of toxoplasmosis in those who have poor immune function. Additionally, it has been used for acne as well as other skin conditions. Moreover it is employed as an anti-inflammatory drug, anti-infective drug, a leprostatic drug and an antimalarial drug.
Patel AP, Patil AS. Dapsone for immune thrombocytopenic purpura in children and adults.Therapeutic drug monitoring.2014,36(2), 261-263.
B.L. Maloff, et al. Dapsone inhibits LTB4 binding and bioresponse at the cellular and physiologic levels.Eur. J. Pharmacol.1988158(1-2), 85-89.
Dichiarazioni di rischio (UE): H302
Harmful if swallowed.
Dichiarazioni precauzionali: P261
Avoid breathing dust/fume/gas/mist/vapours/spray.