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17857-14-6 - (3-Carboxypropyl)triphenylphosphonium bromide, 97% - A19302 - Alfa Aesar

A19302 (3-Carboxypropyl)triphenylphosphonium bromide, 97%

Codice CAS
17857-14-6
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
25g 53,90
100g 152,00
500g 592,00
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(3-Carboxypropyl)triphenylphosphonium bromide, 97%

MDL
MFCD00274196
EINECS
000-000-0

Proprietà chimiche

Formula
HO2C(CH2)3P(C6H5)3Br
Peso formula
429.30
Punto di fusione
244-250°
Sensibilità
Hygroscopic
Solubilità
Soluble in water. soluble in ethanol.

Applicazioni

Reactant for preparation of Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity, Boron-containing benzoxaboroles as antimalarial agents, Methyl alkenyl quinolones as antimycobacterial agents, Solandelactone E via Sharpless epoxidation, Taber cyclopropanation, chemoselective reductions and lithiation-borylation-allylation sequence, Organotin compounds as antifungal agents, Oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B for negative regulation of insulin pathway (a promising target for treatment of diabetes and obesity), 11-oxa prostaglandin analogs with ocular hypotensive activity.

Note

Hygroscopic. Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, water, moisture.

Letteratura

Yu Luo et. al. Synthesis and biological evaluation of piperamide analogues as HDAC inhibitors. Bioorganic & Medicinal Chemistry Letters,. 2011, 21 (16), 4844-4846 .

Yong-Kang Zhang et. al. Synthesis and structure-activity relationships of novel benzoxaboroles as a new class of antimalarial agents. Bioorganic & Medicinal Chemistry Letters,. 2011, 21(2), 644-651 .

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
4173599
Codice tariffe armonizzato
2931.90
TSCA
No

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