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3250-74-6 - 5-(3-Pyridyl)-1H-tetrazole, 98% - 3-[1(2)H-Tetrazol-5-yl]pyridine - B20492 - Alfa Aesar

B20492 5-(3-Pyridyl)-1H-tetrazole, 98%

Codice CAS
3250-74-6
Sinonimi
3-[1(2)H-Tetrazol-5-yl]pyridine

Dimensioni Prezzo ($) Quantità Disponibilità
1g 73,30
5g 294,00
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5-(3-Pyridyl)-1H-tetrazole, 98%

MDL
MFCD00040281
EINECS
426-810-8

Proprietà chimiche

Formula
C6H5N5
Peso formula
147.14
Punto di fusione
ca 240° dec.
Solubilità
Soluble in water (slightly).

Applicazioni

5-(3-Pyridyl)-1H-tetrazole is used as a pharmaceutical intermediate. The Pyridine,3-(2H-tetrazol-5-yl)- acts as reactant with 1-(4-bromo-phenyl)-3-piperidino-propan-1-one, hydrochloride, and obtain the 1-(4-bromo-phenyl)-3-(5-pyridin-3-yl-tetrazol-2-yl)-propan-1-one. This reaction needs the solvent of dimethylformamide. The yield is 31%. In addition, this reaction should be taken for 8 hours at the temperature of 150°C.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Stable under recommended storage conditions. Keep away from strong oxidizing agents.

Letteratura

H X Xue.; XS Wang.; LZ Wang.; RG Xiong. Hydrothermal preparation of novel Cd (II) coordination polymers employing 5-(4-pyridyl) tetrazolate as a bridging ligand. Inorg. Chem. 200241 ( 25), 6544-6546.

EK Moltzen.; H Pedersen.; KP Boegesoe. Bioisosteres of Arecoline: 1,2,3,6-Tetrahydro-5-pyridyl-Substituted and 3-Piperidyl-Substituted Derivatives of Tetrazoles and 1,2,3-Triazoles. Synthesis and Muscarinic Activity. J. Med. Chem. 199437 ( 24), 4085-4099.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H318

Causes serious eye damage.

Dichiarazioni precauzionali: P260u-P201-P280d-P280g-P303+P361+P353-P305+P351+P338-P301+P330+P331-P304+P340-P405-P501a

Obtain special instructions before use. Wear protective clothing and eye protection. Wear protective gloves. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2933.99
TSCA
No

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