Informativa e consenso per l'uso dei cookie

Accetto Il nostro sito salva piccoli pezzi di informazioni (cookie) sul dispositivo, al fine di fornire contenuti migliori e per scopi statistici. È possibile disattivare l'utilizzo di cookies modificando le impostazioni del tuo browser. Continuando la navigazione si acconsente all'utilizzo dei cookie.

37052-78-1 - 2-Mercapto-5-methoxybenzimidazole, 99% - 5-Methoxy-2-benzimidazolethiol - 5-Methoxy-2-mercaptobenzimidazole - B20570 - Alfa Aesar

B20570 2-Mercapto-5-methoxybenzimidazole, 99%

Codice CAS
37052-78-1
Sinonimi
5-Methoxy-2-benzimidazolethiol
5-Methoxy-2-mercaptobenzimidazole

Dimensioni Prezzo ($) Quantità Disponibilità
5g 24,30
25g 93,60
100g 337,00
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

2-Mercapto-5-methoxybenzimidazole, 99%

MDL
MFCD00134581
EINECS
253-326-2

Proprietà chimiche

Formula
C8H8N2OS
Peso formula
180.23
Punto di fusione
255-259°
Sensibilità
Air Sensitive
Solubilità
Soluble in dimethyl sulfoxide. Slightly soluble in methanol. Insoluble in water.

Applicazioni

2-Mercapto-5-methoxybenzimidazole is used in the preparation of COX-2 inhibitors. It is also employed in the preparation of compounds such as 5-methoxy-2-[[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfonyl]-1H-benzimidazole and 5-methoxy-2-[[(4-methoxy-3,5-dimethylpyridin-2-yl-1-oxide)methyl]sulfonyl]-1H-benzimidazole. Further, it acts as a hetercocyclic building block and serves as an intermediate of drug omeprazole.

Note

Air sensitive. Store in a cool place. Incompatible with strong oxidizing agents, acids, bases and reducing agents.

Letteratura

Sawant, R.; Kawade, D. Synthesis and biological evaluation of some novel 2-phenyl benzimidazole-1-acetamide derivatives as potential anthelmintic agents. Acta Pharm. 2011, 61 (3), 353-361.

Joseph, K. M.; Larraza-Sanchez, I. Synthesis of benzyl bromides with hexabromoacetone: an alternative path to drug intermediates. Tetrahedron Lett. 2011, 52 (1), 13-16.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
3605123
Codice tariffe armonizzato
2933.99
TSCA
No

Raccomandato

  • A10622

    1-Nitroso-2-naphthol, 99%
  • A11031

    4'-Ethoxyacetophenone, 98%
  • A13846

    4-Aminoantipyrine, 97%
  • A15218

    Tetra-n-heptylammonium bromide, 99%
  • L19453

    2-Chloromethyl-4-methoxy-3,5-dimethylpyridine hydrochloride, 98%

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio