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2868-37-3 - Methyl cyclopropanecarboxylate, 98% - Cyclopropanecarboxylic acid methyl ester - B20853 - Alfa Aesar

B20853 Methyl cyclopropanecarboxylate, 98%

Codice CAS
2868-37-3
Sinonimi
Cyclopropanecarboxylic acid methyl ester

Dimensioni Prezzo ($) Quantità Disponibilità
25g 20,90
100g 61,50
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Methyl cyclopropanecarboxylate, 98%

MDL
MFCD00001280
EINECS
220-690-9

Proprietà chimiche

Formula
C5H8O2
Peso formula
100.12
Punto di ebollizione
118-119°
Punto di infiammabilità
22°(71°F)
Densità
0.983
Indice di rifrazione
1.4180
Solubilità
Not miscible or difficult to mix in water.

Applicazioni

It is primarily used an intermediate in the manufacture of pharmaceutical and agrochemical products. Methyl cyclopropane carboxylate is used as a reagent in the synthesis of N’-thiazole and N-pyrazole based inhibitors of MAP kinase p38α.

Note

Store away from oxidizing agents and ignition sources. Keep the container tightly closed and place it in a cool, dry and well ventilated condition. Protect from electrostatic charges.

Letteratura

Matthäus Getlik, et al. Structure-based design, synthesis and biological evaluation of N-pyrazole, N?-thiazole urea inhibitors of MAP kinase p38α.Eur. J. Med. Chem.2012481-15.

Roseann Kroeker Sachs, et al. 3-Carbomethoxycyclopropen-3-yl Anion. Formation and Characterization of an Antiaromatic Ion. J. Am. Chem. Soc.,1994,116(2), 783-784.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H225-H331-H302-H319

Highly flammable liquid and vapour. Toxic if inhaled. Harmful if swallowed. Causes serious eye irritation.

Dichiarazioni precauzionali: P210-P261-P280-P240-P303+P361+P353-P305+P351+P338-P304+P340-P311-P405-P501a

Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. Ground/bond container and receiving equipment. IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or doctor/physician. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
2039388
Classe di rischio
3
Gruppo di imballaggio
II
Codice tariffe armonizzato
2916.20
TSCA
Yes

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