2-Bromo-4,6-dimethylaniline can react with 3-chloro-3-methyl-but-1-yne to produce 2-bromo-N-(1',1'-dimethylprop-2'-ynyl)-4,6-dimethylaniline. This reaction will need reagent Et3N, catalyst CuCl, and the menstruum dioxane.
Rattan K. Gujadhur.; Craig G. Bates.; D. Venkataraman. Formation of Aryl-Nitrogen, Aryl-Oxygen, and Aryl-Carbon Bonds Using Well-Defined Copper(I)-Based Catalysts. Org. Lett. 2001, 3, (26), 4315-4317.
Fuk Yee Kwong.; Artis Klapars.; Stephen L. Buchwald. Copper-Catalyzed Coupling of Alkylamines and Aryl Iodides:? An Efficient System Even in an Air Atmospheres. Org. Lett. 2002, 4, (4), 581-584.
Dichiarazioni di rischio (UE): H302-H312-H331-H315-H319-H373
Harmful if swallowed. Harmful in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye irritation. May cause damage to organs through prolonged or repeated exposure.
Dichiarazioni precauzionali: P260-P201-P280g-P304+P340-P405-P501a
Do not breathe dust/fume/gas/mist/vapours/spray. Obtain special instructions before use. Wear protective gloves. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.