Informativa e consenso per l'uso dei cookie

Accetto Il nostro sito salva piccoli pezzi di informazioni (cookie) sul dispositivo, al fine di fornire contenuti migliori e per scopi statistici. È possibile disattivare l'utilizzo di cookies modificando le impostazioni del tuo browser. Continuando la navigazione si acconsente all'utilizzo dei cookie.

119-65-3 - Isoquinoline, 97+% - B21279 - Alfa Aesar

B21279 Isoquinoline, 97+%

Codice CAS
119-65-3
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
100g 51,75
500g 147,20
2500g 489,52
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

Isoquinoline, 97+%

MDL
MFCD00006898
EINECS
204-341-8

Proprietà chimiche

Formula
C9H7N
Peso formula
129.16
Punto di fusione
24-27°
Punto di ebollizione
241-243°
Punto di infiammabilità
107°(225°F)
Densità
1.090
Indice di rifrazione
1.6245
Solubilità
Soluble in water (5g/L).

Applicazioni

Isoquinoline is used in the manufacture of dyes, paints, antifungal. It is also used as a solvent for the extraction of resins and terpenes.

Note

Store away from strong oxidizing agents. Keep container tightly closed. Store in cool, dry conditions in well sealed containers.

Letteratura

Maria Chrzanowska.; Maria D. Rozwadowska. Asymmetric Synthesis of Isoquinoline Alkaloids. Chem. Rev. 2004, 104, (7), 3341-3370.

Ryoji. Noyori.; Masako. Ohta.; Yi. Hsiao.; Masato. Kitamura.; Tetsuo. Ohta.; Hidemasa. Takaya. Asymmetric synthesis of isoquinoline alkaloids by homogeneous catalysis. J. Am. Chem. Soc. 1986, 108, (22), 7117-7119.

Reacts with various acid halides in the presence of CN- to give "Reissert compounds" (1-cyano-2-acyl 1,2-dihydro derivatives). For reviews, see: Chem. Rev., 55, 511 (1955); Adv. Het. Chem., 9, 1 (1968); 24, 187 (1979). 1-Alkylisoquinolines can be prepared by alkylation of the Li or Na derivatives of Reissert compounds: Org. Synth. Coll., 4, 641 (1963); 6, 115 (1988). For formation of Reissert compounds from a variety of carbonyl, sulfonyl and phosphoryl halides under milder, phase-transfer conditions, see: Synthesis, 497 (1977). For 'direct' cyanation by a modified Reissert procedure in the presence of tosyl chloride followed by DBU, see: J. Org. Chem., 49, 4056 (1984).

A one-step synthesis of 1-nitroisoquinoline has been reported in which isoquinoline reacts with KNO2 in the presence of acetic anhydride and DMSO. The reaction is considered to be analogous to the Pfitzner-Moffatt oxidation (see Dimethyl­ sulfoxide, A13280): J. Chem. Soc., Perkin 1, 1777 (1996).

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H311-H302-H315-H319

Toxic in contact with skin. Harmful if swallowed. Causes skin irritation. Causes serious eye irritation.

Dichiarazioni precauzionali: P280-P305+P351+P338-P361-P362-P301+P312-P312-P363-P321-P405-P501a

Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Remove/Take off immediately all contaminated clothing. Take off contaminated clothing and wash before reuse. IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. Wash contaminated clothing before reuse. Specific treatment (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Merck
14,5222
Beilstein
107549
Classe di rischio
6.1
Gruppo di imballaggio
II
Codice tariffe armonizzato
2933.49
TSCA
Yes
RTECS
NW6825000

Raccomandato

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio