Autorizzo l’utilizzo di cookies.

Accetto Utilizziamo cookies per migliorare il nostro servizio e realizzare statistiche. Questa funzione puó essere disattivata cambiando la configurazione del browser. Continuando a navigare senza modificare questi parametri, consideriamo che l’uso di cookies sia accettato

375-72-4 - Nonafluorobutanesulfonyl fluoride, 90+% - Nonaflyl fluoride - Perfluorobutanesulfonyl fluoride - B21322 - Alfa Aesar

B21322 Nonafluorobutanesulfonyl fluoride, 90+%

Codice CAS
375-72-4
Sinonimi
Nonaflyl fluoride
Perfluorobutanesulfonyl fluoride

Dimensioni Prezzo ($) Quantità Disponibilità
5g 23,40
25g 70,20
100g 203,00
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

Nonafluorobutanesulfonyl fluoride, 90+%

MDL
MFCD00007422
EINECS
206-792-6

Proprietà chimiche

Formula
CF3(CF2)3SO2F
Peso formula
302.09
Punto di fusione
-110°
Punto di ebollizione
65-66°
Punto di infiammabilità
None
Densità
1.750
Indice di rifrazione
1.2810
Sensibilità
Moisture Sensitive
Solubilità
Hydrolyses in water.

Applicazioni

Benzynes were generated from o-(trimethylsilyl) phenols using nonafluorobutanesulfonyl fluoride (NfF) by a domino process.Nonafluorobutanesulfonyl fluoride (nonaflyl fluoride, C 4 F 9 SO 2 F, NfF) is the most widely used commercially available reagent for the synthesis of nonaflates.

Note

Store in cool place. Keep container tightly closed in a dry and well-ventilated place. Store away from strong oxidizing agents, moisture, baese..

Letteratura

Takashi Ikawa,; Tsuyoshi Nishiyama,; Toshifumi Nosaki,; Akira Takagi,; Shuji Akai. A Domino Process for Benzyne Preparation: Dual Activation of o-(Trimethylsilyl)phenols by Nonafluorobutanesulfonyl Fluoride. Org. Lett., . 2011, 13 (7), 730-1733.

Jens Högermeier,; Hans-Ulrich Reissig. Nine Times Fluoride can be Good for your Syntheses. Not just Cheaper: Nonafluorobutanesulfonates as Intermediates for Transition Metal-Catalyzed Reaction. Advanced Synthesis & Catalysis. 2009, 351 (17), 2747-2763.

Reagent for formation of nonafluorobutanesulfonates (nonaflates) of OH groups (compare Trifluoromethanesulfonic anhydride, A11767), e.g. with triethylamine in ether: Synthesis, 293 (1973); Liebigs Ann. Chem., 20 (1973).

Nonaflates of phenols, which are stable to flash chromatography, are attractive precursors for coupling reactions, with alkyl- and arylzinc halides, arylboronic acids (Suzuki) and arylstannanes (Stille), catalyzed by Pd(0) under mild conditions: J. Org. Chem., 63, 203 (1998). Silyl enol ethers, with catalytic TBAF in the presence of molecular sieves, are converted to enol nonaflates which undergo Heck couplings, e.g with styrenes to give 1,3-dienes: Synlett, 1141 (1997).

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H314-H318

Causes severe skin burns and eye damage. Causes serious eye damage.

Dichiarazioni precauzionali: P260u-P201-P280i-P304+P340-P405-P501a

Obtain special instructions before use. Wear eye/face protection. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
1813589
Classe di rischio
8
Gruppo di imballaggio
II
Codice tariffe armonizzato
2904.99
TSCA
Yes

Raccomandato

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio