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Ethyl bromofluoroacetate is used as an intermediate useful in the synthesis of polyfluoroalkyl-substituted fluoro enol ethers and N-protected α-fluoroglycines.
R Ocampo.; WR Dolbier.; KA Abboud. Catalyzed Reformatsky reactions with ethyl bromofluoroacetate for the synthesis of α-fluoro-β-hydroxy acids. J. Org. Chem. 200267 (1), 72-78.
Undergoes Reformatsky reactions with Zn and carbonyl compounds under various conditions. Superior results have been obtained in the presence of a catalytic amount of CeCl3: J. Org. Chem., 67, 72 (2002):
Dichiarazioni di rischio (UE): H227-H301-H311-H331-H315-H318-H335
Combustible liquid. Toxic if swallowed. Toxic in contact with skin. Toxic if inhaled. Causes skin irritation. Causes serious eye damage. May cause respiratory irritation.
Dichiarazioni precauzionali: P210u-P261-P301+P310a-P305+P351+P338-P405-P501a
Keep away from heat/sparks/open flames/hot surfaces. - No smoking. Avoid breathing dust/fume/gas/mist/vapours/spray. IF SWALLOWED: Immediately call a POISON CENTER/doctor IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.