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Trichloroacetyl chloride is used in the preparation of dihydro-1H-benzindoles. It is also used in the synthesis of 3-alkylbenzoxazolones It is used in the manufacture of pharmaceuticals and plant protection compounds. It is used for manufacturing the esters and anhydrides of trichloroacetic acid. It is used in the manufacture of pharmaceuticals and organic synthesis intermediate.
Ram N Ram and Vineet Kumar Soni. Synthesis of 3-alkylbenzoxazolones from N-alkyl-N-arylhydroxylamines by contiguous O-trichloroacetylation, trichloroacetoxy ortho-shift, and cyclization sequence.J Org Chem.201378(23), 11935-11947.
Gustavo P Silveira and Joseph P Marino. Enantioselective synthesis of dihydro-1H-benzindoles.J. Org. Chem.201378(7), 3379-3383.
Dichiarazioni di rischio (UE): H302-H330-H314-H318
Harmful if swallowed. Fatal if inhaled. Causes severe skin burns and eye damage. Causes serious eye damage.
Dichiarazioni precauzionali: P303+P361+P353-P304+P340-P305+P351+P338-P320-P405-P501a
IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Specific treatment is urgent (see label). Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.