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98437-23-1 - Benzo[b]thiophene-2-boronic acid, 98% - Thianaphthene-2-boronic acid - B22835 - Alfa Aesar

B22835 Benzo[b]thiophene-2-boronic acid, 98%

Codice CAS
98437-23-1
Sinonimi
Thianaphthene-2-boronic acid

Dimensioni Prezzo ($) Quantità Disponibilità
1g 20,48
5g 64,87
25g 216,90
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Benzo[b]thiophene-2-boronic acid, 98%

MDL
MFCD01075674

Proprietà chimiche

Formula
C8H7BO2S
Peso formula
178.02
Punto di fusione
ca 255°
Solubilità
Insoluble in water.

Applicazioni

Benzo[b]thiophene-2-boronic acid is used in the synthesis of phosphorescent sensor for quantification of copper(II) ion, UV promoted phenanthridine syntheses, Preparation of CYP11B1 inhibitors for treatment of cortisol dependent diseases, PDE4 inhibitors, Suzuki-Miyaura cross-coupling reactions.

Note

Store in cool, dry conditions in a sealed container. Incompatible with oxidizing agents.

Letteratura

Frédéric J.J. Bihel; Hélène Justiniano; Martine Schmitt; Malik Hellal; Mohamed A. Ibrahim; Claire Lugnier; Jean-Jacques Bourguigno. New PDE4 inhibitors based on pharmacophoric similarity between papaverine and tofisopam. Bioorganic & Medicinal Chemistry Letters. 2011, 21 (21), 6567-6572.

Partha S. Banerjee; Edison S. Zuniga; Iwao Ojima; Isaac S. Carrico. Targeted and armed oncolytic adenovirus via chemoselective modification. Bioorganic & Medicinal Chemistry Letters. 2011, 21, (17), 4985-4988.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
1637924
Codice tariffe armonizzato
2934.99
TSCA
No

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