Autorizzo l’utilizzo di cookies.

Accetto Utilizziamo cookies per migliorare il nostro servizio e realizzare statistiche. Questa funzione puó essere disattivata cambiando la configurazione del browser. Continuando a navigare senza modificare questi parametri, consideriamo che l’uso di cookies sia accettato

94790-37-1 - O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98% - HBTU - B23597 - Alfa Aesar

B23597 O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98%

Codice CAS
94790-37-1
Sinonimi
HBTU

Dimensioni Prezzo ($) Quantità Disponibilità
5g 48,90
25g 180,00
100g 703,00
Aggiungi al carrello Aggiungi al preventivo generale Visualizza articolo

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 98%

MDL
MFCD00075445
EINECS
423-020-5

Proprietà chimiche

Formula
C11H16F6N5OP
Peso formula
379.25
Punto di fusione
ca 200° dec.
Solubilità
Soluble in acetonitrile.

Applicazioni

O-(1H-Benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate is used as a coupling reagent for solid-phase peptide synthesis. It has been shown to effectively suppress racemization.

Note

Store in a cool place. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with oxidizing agents.

Letteratura

Peptide coupling reagent giving high yields with minimal racemization: Synthesis, 572 (1984). See Appendix 6.

Yoshida, M.; Sasahara, K. I.; Doi, T. Total synthesis of cyclodepsipeptide spiruchostatin A on silyl-linked polymer-support. Tetrahedron 2015, 71 (40), 7647-7653.

Buba, A. E.; Löwe, H.; Kunz, H. Fluorenylmethoxycarbonyl-Protected O-Glycosyl-N-methyl Amino Acids: Building Blocks for the Synthesis of Conformationally Tuned Glycopeptide Antigens. Eur. J. Org. Chem. 2015, 2015 (26), 5764-5774.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280a-P305+P351+P338-P304+P340-P405-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves and eye/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Store locked up. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Beilstein
7328329
Codice tariffe armonizzato
2933.99
TSCA
No

Raccomandato

  • A10807

    1-(3-Dimethylaminopropyl)-3-ethylcarbodiimide hydrochloride, 98+%
  • A11801

    N-Ethyldiisopropylamine, 99%
  • A13016

    4-(Dimethylamino)pyridine, 99%
  • A13280

    Dimethyl sulfoxide, 99+%
  • H26082

    O-(7-Aza-1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate, 99%

Visualizzati di recente

Prodotti chimici

Scienze della vita

Metalli e materiali

Catalizzatori

Apparecchiature di analisi e di laboratorio