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1737-36-6 - 4-Chloro-3-(trifluoromethyl)benzoic acid, 97+% - B23656 - Alfa Aesar

B23656 4-Chloro-3-(trifluoromethyl)benzoic acid, 97+%

Codice CAS
1737-36-6
Sinonimi

Dimensioni Prezzo ($) Quantità Disponibilità
1g 64,10
5g 228,00
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4-Chloro-3-(trifluoromethyl)benzoic acid, 97+%

MDL
MFCD01631468

Proprietà chimiche

Formula
C8H4ClF3O2
Peso formula
224.57
Punto di fusione
163-165°
Solubilità
Slightly soluble in water at 25°C 0.039 g/L.

Applicazioni

It is used in the synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.

Note

Store away from oxidizing agents. Keep the container tightly closed and place it in a cool, dry and well ventilated condition.

Letteratura

Myung-Ho Jung, et. al. Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.Bioorg. Med. Chem. Lett.,2009,19(23), 6538-6543.

Mohammed Ibrahim El-Gamal, et. al. Diarylureas and Diarylamides with Pyrrolo[2,3-d]pyrimidine Scaffold as Broad-Spectrum Anticancer Agents.Chem. Pharm. Bull.,2014,62(1), 25-34.

Rischio GHS e dichiarazioni precauzionali

Dichiarazioni di rischio (UE): H315-H319-H335

Causes skin irritation. Causes serious eye irritation. May cause respiratory irritation.

Dichiarazioni precauzionali: P261-P280-P305+P351+P338-P304+P340-P362-P312-P321-P405-P403+P233-P501a

Avoid breathing dust/fume/gas/mist/vapours/spray. Wear protective gloves/protective clothing/eye protection/face protection. IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. Take off contaminated clothing and wash before reuse. Call a POISON CENTER or doctor/physician if you feel unwell. Specific treatment (see label). Store locked up. Store in a well-ventilated place. Keep container tightly closed. Dispose of contents/container in accordance with local/regional/national/international regulations.

Altri riferimenti

Codice tariffe armonizzato
2916.39
TSCA
No

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